| Key
Facts |
- Acute insult resulting
in diffuse alveolar damage (DAD)
- Homogenous diffuse
ground glass opacities
- Rapid development,
usually intubated at diagnosis
- Synonym: Haman-Rich
Syndrome
|
| Imaging
Findings |
Chest
Radiograph
- Diffuse consolidation,
intubated
CT/HRCT
- Diffuse ground
glass opacities to consolidation
- Central airways
may be dilated
- No pleura fluid
or adenopathy
|
| Differential
Diagnosis |
- CHF
- Drug reaction
- Renal failure
- Viral pneumonia
- Diffuse hemorrhage
|
| Pathological
Features |
- Unknown insult
to alveolar wall
- Temporally homogeneous
- Pathologic findings
of diffuse alveolar damage
|
| Clinical
Presentation |
- Acute fever, cough,
SOB rapidly progress to respiratory failure (days)
- Diagnosis of exclusion,
exclude drugs and toxins
- Supportive care,
oxygen, steroids
- Prognosis poor,
mortality 80%
|
| References |
Primack
SL et al. Acute interstitial pneumonia: radiographic and CT findings in
nine patients. Radiology 188: 817-20, 1993.
|
