Mosaic Perfusion

Key Facts
  • Inhomogeneous lung attenuation (ground glass) due to either patchy airspace obstruction with reduced ventilation or chronic vascular obstruction
  • Decreased size of blood vessels in blacker lung helpful and points to vascular obstruction as cause
Pattern
  • Look for abnormal airways, dilated or thickened walls as cause of airways obstruction
  • Mosaic attenuation due to airways disease usually smaller (lobular) and more sharply defined
  • Mosaic attenuation due to vascular disease less distinct and involve larger areas
  • Expiratory scans usually to demonstrate air-trapping in airways disease
  • "Head-Cheese sign"
Differential Diagnosis
  • Chronic PE
  • Pulmonary hypertension
  • Bronchiolitis obliterans
  • Bronchiectasis
  • Hypersensitivity pneumonitis
  • Vasculitis
References

Stern EJ et al.: CT mosaic pattern of lung attenuation: etiologies and terminology. J Thorac Imaging 10:294-297, 1995.